Senior Bioinformatician - Cancer Dependency Map Analytics

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Salary £36,373 to £44,011, depending on experience plus excellent benefits

Fixed term for 3 years

The Wellcome Sanger Institute is seeking for an experienced Bioinformatician to provide computational support to the international Cancer Dependency Map consortium, and to other projects engaged in the analysis of data from genome-editing and functional-genomics screens, in collaboration with Open Targets.

The selected candidate will join the Cancer Dependency Map Analytics team, actively interacting with the Cancer Dependency Mapconsortium, whose broad goal is to identify vulnerabilities and dependencies that could be exploited therapeutically in every cancer cell.

The successful candidate will be able to extensively use computational pipelines for pre-processing and quality control assessment of data from genome-editing screens, and to implement new analytical pipelines on an individual project needs' basis extending existing software, writing, documenting and maintaining code packages on public/internal repositories. Past experience with genomic data curation and familiarity with the management of data from large-scale in-vitro drug/functional-genomic screens will be positively considered.

Finally, the selected candidate will interact with Open Targets partners and collaborators, and with web development teams to coordinate data/results flows on the public domain.

This position offers the opportunity to work at one of the world's leading genomic centres at the forefront of genomic research. The successful candidate will have access to Sanger's computational resources, including a 15000+ core computational cluster, the largest in life science research in Europe, and multiple petabytes of high-speed cluster file systems.

We are part of a dynamic and collaborative environment at the Genome Campus and, although we seek someone who can work independently, the selected candidate will have the opportunity to interact with researchers across many programmes at the Institute.

Francesco Iorio - Please contact for informal enquiries

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity's greatest challenges.

Genome Research Limited is an Equal Opportunity employer. As part of our commitment to equality, diversity and inclusion and promoting equality in careers in science, we hold an Athena SWAN Bronze Award and have an active Equality, Diversity and Inclusion programme of activity. We will consider all applicants without discrimination on grounds of disability, sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. We are open to a range of flexible working options including part-time or full-time employment as well as flexible hours due to caring or other commitments.

Please include a covering letter and CV with your application. Closing date for applications: 23rd September 2018.