Senior Bioinformatician - CASM

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An exciting statistical analysis and development opportunity has become available within the Cancer, Ageing and Somatic Mutation Group (CASM). The successful candidate will be embedded in a large multidisciplinary team and will be tasked with further developing our cancer analysis algorithms specifically for cancer predisposition and cancer evolution.

The role involves working closely with scientific/IT staff within CASM to develop novel analysis strategies and actively contribute to the statistical modelling and data analysis of this important study. In addition, the role will also involve improving existing algorithms and developing new software when required as well as analysing whole genome sequencing and single cell data.

The position would suit a Bioinformatician/Statistician who enjoys developing algorithms and statistical modelling to analyse complex NGS biological data sets. We are looking for an individual who enjoys working in a multi-disciplinary team environment, to help solve complex IT issues, which will ultimately aid our analysis of cancer related datasets.

Essential Skills

Degree in Bioinformatics, Mathematics, Statistics or Computer Science with a scientific background.

Software development skills (using Perl and/or Python)

Experience of bioinformatics and familiarity with genome data

Evidence of proficiency in Perl programming or another modern computer language

Strong UNIX/LINUX skills

Experience of working with biological analysis pipelines on multi-node compute clusters

Proficient in statistical analysis of genome-wide datasets

Previous scientific publications

Enjoy working as part of a team

Ideal Skills

PhD in a bioinformatics or mathematics subject

Experience in single cell analysis

LSF or Open Grid scheduling software

R and/or Matlab programming experience

Experience of workflow management IT systems

Experience working, developing and compiling software tools in a UNIX/LINUX environment.

Background in cancer genetics

Evidence of academic excellence

Other information

The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.

Our Campus: Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity's greatest challenges.

Our Benefits: Our employees have access to a comprehensive range of benefits and facilities including:

Defined Contribution Pension Scheme and Life Assurance

Group Income Protection

Private Health Insurance

25 days annual leave, increasing by one day a year to a maximum of 30

Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club

Two days paid Employee Volunteering Leave a year

Employee Discount Scheme

Campus Gym, tennis courts, cricket pitch and sports hall plus a range of dining facilities

Active Campus Sports and Social Club

Free Campus Bus Service

Genome Research Limited hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Please include a covering letter and CV with your application. Closing date for applications: 8th May 2019

Salary in the region of £36,737 - £44,451 (dependent on experience) plus excellent benefits

Fixed term for 5 years